The Tissue Mechanics Laboratory focuses on the development of experimental and computational approaches and their applications in multiphasic and multiscale heterogeneous biomaterials and biological tissues. We seek to understand how the microscopic structures and constituents dictate the macroscopic mechanical characteristics in those multiscale systems.
Our long-term goal is to understand how such microscopic-macroscopic relationships evolve in dynamic systems such as human and animal tissues, both functional (e.g. developmental biology) and dysfunctional (e.g. human cancer), and porous scaffolds for tissue engineering. With in-depth understanding of the mechanisms that regulate the concurrent evolutions of the microscopic structural constituents and their macroscopic mechanical characteristics, we hope to make translational impact in areas such as cancer diagnosis, medical devices and tissue engineering.